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耿巧红,副教授,2007年毕业于山东大学,获硕士学位。主要从事功能有机分子的设计与合成及分析检测方向研究,近年来先后在Bioorganic & Medicinal Chemistry letters,Bioorganic Chemistry,Current Medicinal Chemistry,Journal of the American Chemical Society,Journal of Materials Chemistry B,International Journal of Oncology等期刊上等杂志发表研究论文10余篇。主讲分析化学、分析化学实验、仪器分析等课程,指导学生获得全国大学生化学创新设计竞赛二等奖,获得全国大学生华北赛区化学创新设计竞赛一等奖。
研究方向
1. 功能有机分子的设计与合成
2. 分析检测技术研究
主持和参与课题
1、 小分子PD-L1拮抗剂的设计、合成及其抗肿瘤作用机制研究,山东省自然科学基金-面上项目,10万,ZR2020MB013,2021.01-2023.12,在研(主持人)
2、 基于产教融合的环境监测实训课程教学改革,国家教育部产学结合教学内容和课程体系改革,202101255021,2021.06-2022.06,在研(主持人)
发表论文
1. Maosheng Wan1, 3 ,Yanglin Luo2 ,Zhangfa Tong3 , Qiaohong Geng4* , Li Hua1,Novel Amino Acid-stilbene Quaternary Ammonium Salt Fluorescent Whitening Agents: Synthesis, Optical Properties, Acid Resistance and Antibacterial Activity, coloration technology, 2021,Accepted.
2. Qiaohong Geng#, Sagar O. Rohondia, Harras J. Khan, Peifu Jiao*, Q. Ping Dou*: Small molecules as antagonists of co-inhibitory pathways for cancer immunotherapy: a patent review (2018-2019), Expert Opinion On Therapeutic Patents, 2020, 30 (9), 677-694. (Sep 08, 2020, SCI, IF=5.611 (2019), 中科院2区)
3. Peifu Jiao, Qiaohong Geng*, Peng Jin, Gaoxing Su, Houyun Teng, Jinlong Dong, Bing Yan*: Small molecules as PD-1/PD-L1 pathway modulators for cancer immunotherapy, Current Pharmaceutical Design, 2018, 24(41), 4911-4920. (Nov 11, 2018, SCI, IF=2.208 (2019), 中科院3区)
4. Qiaohong Geng#, Peifu Jiao*, Peng Jin, Gaoxing Su, Jinlong Dong, Bing Yan*:PD-1/PD-L1 inhibitors for immuno-oncology: From antibodies to small molecules, Current Pharmaceutical Design, 2017, 23(39), 6033-6041. (Oct 04, 2017, SCI, IF=2.208 (2019), 中科院3区)
5. Peifu Jiao, Peng Jin, Chencan Li, Lechao Cui, Lihua Dong, Bin Pan, Wentong Song, Liang Ma, Jinlong Dong, Lei Song, Xinjie Jin, Faming Li, Maosheng Wan*, Zhitao Lv*, Qiaohong Geng*: Design, synthesis and in vitro evaluation of amidoximes as histone deacetylase inhibitors for cancer therapy, Bioorganic & Medicinal Chemistry letters, 2016, 26(19), 4679-4683. (Oct 01, 2016, SCI, IF=2.572 (2019), 中科院3区)
专利
1.耿巧红,焦培福;一种作为免疫调节剂的小分子非核苷类化合物,2021,中国发明专利,专利号/公开号:CN112920132A;
奖励
1.第二届全国大学生化学实验创新设计竞赛二等奖,2021,中国化学会
2. 全国大学生华北赛区化学实验创新设计竞赛一等奖,2021,中国化学会