李雅文，讲师，2020年毕业于华东理工大学获博士学位。2018年赴德国Jacobs University Bremen交流学习。科研方面：在胶体界面化学与生物医学工程交叉方向，针对药物控释传递和靶向传递的关键问题，从事中药纳米药物载体的构建和抗肿瘤活性研究的研究。近年来先后在Colloids and Surfaces B: Biointerfaces, Langmuir等杂志发表多篇研究论文。主讲《物理化学》、《物理化学实验》、《化妆品工艺学》、《专业英语与文献检索》课程。
研究方向
1. 脂质纳米药物载体
2. 化妆品功效成分的包裹与功效评价
主持和参与课题
1. 新型多功能中药溶致液晶载药系统的构建及其抗肿瘤作用的研究(No. 21573070)，国家自然科学基金面上项目，参与，2016.1-2019.12，79万。
2. 基于上海同步辐射光源的生物小角X-射线散射技术在膜蛋白结构生物学应用中关键技术的研究” (No. U1832144），国家自然科学基金大科学装置科学研究联合基金，参与，2019.01-2022.12，65万。
发表论文
1. Shuyang Tu#, Haijiao Zhang#, Yawen Li#, Yongchao Zhang, Qiang Tian, László Almásy, Xianhui Xu, Rongguang Zhang, Aihua Zou *, Na Li *. A practical method to quantify the inhomogeneous biological membrane structures using small-angle scattering technique. Applied Sciences. 2021, 11(15), 6965.
2. Yawen Li, Angelina Angelova, Fangzhou Hu, Vasil M. Garamus, Changjun Peng, Na Li, Janwen Liu, Dan Liu, Aihua Zou*. pH-Induced Inverted Hexagonal-to-Cubic Phase Transition in Lyotropic Liquid Crystalline Carriers of Brucea Javanica Oil and Doxorubicin. Langmuir, 2019, 35, 14532−14542.
3. Yawen Li, Angelina Angelova, Jianwen Liu; Vasil M. Garamus, Na Li, Markus Drechsler, Yabin Gong, Aihua Zou*. In situ phase transition of microemulsions for parenteral injection yielding lyotropic liquid crystalline carriers of the antitumor drug bufalin. Colloids and Surfaces B: Biointerfaces, 2019, 173:217-225.
4. Aihua Zou*#, Yawen Li#, Yiyin Chen, Angelina Angelova, Vasil M. Garamus, Na Li, Markus Drechsler, BorislavAngelov, Yabin Gong. Self-assembled stable sponge-type nanocarries for Brucea javanica oil delivery. Colloids and Surfaces B: Biointerfaces, 2017, 153:310–319.
5. Angelina Angelova, Vasil M. Garamus, Borislav Angelov, Zhenfen Tian, Yawen Li, Aihua Zou*. Advances in structural design of lipid-based nanoparticle carriers for delivery of macromolecular drugs, phytochemicals and anti-tumor agents. Advances in Colloid and Interface Science, 2017, 249: 331-345.
6. Dan Liu, Angelina Angelova, Jianwen Liu, Vasil M. Garamus, Borislav Angelov, Xinlei Zhang, Yawen Li, Guillaume Feger, Na Li*, Aihua Zou*. Self-Assembly of Mitochondria-Specific Peptide Amphiphiles Amplifying the Lung Cancer Cell Death through Targeting the VDAC1-Hexokinase-II Complex. Journal of Materials Chemistry B, 2019, 7: 4706-4716.
专利
龚亚斌，邹爱华，李雅文，蟾毒灵溶致液晶载体、原料组合物及制备方法，201710258425.6
